Table 1.
Cell viability of HSC-2 and gingival fibroblasts at varying concentrations of SCFA.
| Cell Type | HSC-2 Cell Line | Gingival Fibroblasts | ||||
|---|---|---|---|---|---|---|
| Concentration | Acetate | Propionate | Butyrate | Acetate | Propionate | Butyrate |
| 100 mM | 39.2 ± 5 | 46.4 ± 5.1 | 53.5 ± 5 | 12.5 ± 1.2 | 11.9 ± 1.5 | 10.1 ± 0.9 |
| 30 mM | 45.8 ± 5.9 | 56.6 ± 5.8 | 95.8 ± 6 | 69.8 ± 4.5 | 74.5 ± 2.1 | 94 ± 0.5 |
| 10 mM | 104.7 ± 6.1 | 113 ± 6.4 | 122.7 ± 6.5 | 96.3 ± 1.2 | 102.7 ± 1.2 | 122.3 ± 3.1 |
| 1 mM | 125 ± 7.0 | 136 ± 5.6 | 139 ± 7.7 | 125.3 ± 6.7 | 130.4 ± 0.5 | 135.5 ± 6.5 |
HSC-2 cells and gingival fibroblasts exposed at different concentration of SFCA. Cell viability is represented by formazan production indicated in percentage of unstimulated controls ± SD. Cells maintained their viability with up to 10 mM of acetate and propionate, and up to 30 mM of butyrate.