Table 2.
Deregulated miRNAs associated directly or indirectly with MYC expression in gastric cancer.
| miRNA | miRNA Expression | MYC Expression | Reference | |
|---|---|---|---|---|
| miR-9 | Up | Up | [82,83] | |
| miR-15a/16-1 | Down | Up | [84,85] | |
| miR-25 | Up | Up | [86,87] | |
| Cluster miR-17-92 | miR-17 | Up | Up | [87,88] |
| miR-18a | Up | Up | [87,89] | |
| miR-19a/miR-19b | Up | Up | [87,90] | |
| miR-20 | Up | ? | [87] | |
| miR-22 | Down | ? | [91] | |
| miR-26 | Down | Up | [92] | |
| miR-29 | Down | ? | [93] | |
| miR-33b | Down | Down | [94] | |
| miR-34a | Down | Up | [95,96] | |
| miR-92 | Down | ? | [97] | |
| miR-93 | Up | Down | [98] | |
| miR-101 | Down | Up | [99] | |
| miR-106a/miR-106b | Up | ? | [87,100] | |
| miR-150 | Down | Up | [101] | |
| miR-152 | Down | [102] | ||
| miR-185 | Down | Up | [103] | |
| miR-186 | Down | ? | [104] | |
| miR-200c | Down | ? | [105] | |
| miR-212 | Up | Up | [106] | |
| miR-363 | Down | Up | [106] | |
| miR-374 | Up | ? | [107] | |
| miR-429 | Down | Up | [108] | |
| miR-494 | Down | Up | [109] | |
| miR-520d-3p | Down | Up | [110] | |
| miR-561 | Down | Up | [111] | |
| miR-935 | Up | Up | [112] | |
| miR-1284 | Down | ? | [113] | |
| let-7a | Up | Up | [114] | |
Up, upregulated expression in gastric cancer in relation to control; Down, downregulated expression in gastric cancer in relation to control; ?: absence of studies on direct relationship between the respective microRNA and MYC in gastric cancer.