Table 4.

QUIPS tool for assessing risk of bias in the clinical studies.

Study	QUIPS
	Study Participation	Study Attrition	Prognostic Factor Measurement	Outcome Measurement	Confounding Measurement and Account	Analysis
PLT functions/features and growth factor in PLTs during osteoporosis
Kim et al.2011 [43]	Low	Low	Moderate	Moderate	Moderate	Low
Li et al. 2012 [44]	Low	Low	Low	Moderate	Low	Low
D’Amelio et al. 2012 [45]	Moderate	High	Moderate	High	Moderate	Moderate
Akbal et al. 2014 [32]	Low	Low	Low	Moderate	Low	Low
Kim et al. 2015 [34]	Low	Low	Low	Low	Low	Low
Aypak et al. 2016 [46]	Low	Low	Low	Moderate	Moderate	Moderate
Tang et al. 2017 [42]	Low	Moderate	Moderate	Moderate	Moderate	Moderate
Vural et al. 2017 [47]	Low	Low	Low	Moderate	Low	Moderate
Koseoglu et al. 2017 [48]	Low	Low	Low	Moderate	Moderate	Low
Eroglu et al. 2019 [33]	Low	Moderate	High	Moderate	Moderate	Low

low (good) indicator, moderate indicator, high (bad) indicator.