Table 2.

Multivariate Cox regression analysis of five-year and of tumour-specific mortality, and of tumour recurrence.

		Overall Mortality			Tumour-Specific Mortality			Tumour Recurrence
PLR	≥107	1.499			1.499			1.651
NLR	≥3.9		2.122 *			2.122 *			1.800
PLR and NLR aggregately	PLR ≥ 107 and NLR < 3.9			1.153			1.153			1.435
	PLR ≥ 107 and NLR ≥ 3.9			2.291 *			2.291 *			2.180 *
Age a	≥65 years	0.906	1.045	1.018	0.906	1.045	1.018	0.825	0.876	0.860
Gender b	Male	2.460	2.730 *	2.732 *	2.460	2.730 *	2.732 *	3.530 **	3.809 **	3.840 **
Stage c	2	6.690 g	6.802 g	6.616	6.690 g	6.802 g	6.616	2.198	2.269	2.175
	3	7.315 g	7.698 g	7.439	7.315 g	7.698 g	7.439	1.293	1.443	1.306
	4	14.44 *g	13.40 *g	12.87 *	14.44 *g	13.40 *g	12.87 *	2.591	2.733 *	2.447
Grade of differentiation d	2	1.778	1.911	1.941	1.778	1.911	1.941	4.274 *	4.518 *	4.741 *
	3	1.341	1.534	1.540	1.341	1.534	1.540	2.539	2.762	2.854
	4	-	-	-	-	-	-	4.159	4.020	4.845
	Unknown	1.954	2.210	2.237	1.954	2.210	2.237	2.977	3.272	3.393
Location e	Oropharynx	0.817	0.796	0.833	0.817	0.796	0.833	1.285	1.196	1.331
	Oral cavity	0.546	0.549	0.559	0.546	0.549	0.559	12.29 **	13.21 **	13.30 **
	Sub-/supraglottis	1.221	1.152	1.189	1.221	1.152	1.189	1.330	1.160	1.264
	Glottis	0.631	0.560	0.577	0.631	0.560	0.577	1.100	0.991	1.064
	Multiple locations	0.475	0.595	0.593	0.475	0.595	0.593	0.633	0.618	0.676
RBC		0.503 *	0.508 **	0.509 **	0.503 *	0.508 **	0.509 **	0.508 **	0.512 **	0.510 **
Platelet count f	≥400 G/L	0.906	1.045	1.018	0.906	1.045	1.018	0.825	0.876	0.860
Number of patients		156	156	156	156	156	156	148	148	148

The table shows hazard ratios; values over 1 indicate an enhanced risk. ^a Base: <65 years, ^b Base: Female, ^c Base: Stage 1, ^d Base: Grade 1, ^e Base: Hypopharynx, ^f Base: <400 G/L, ^g Wald-test p < 0.05, * p < 0.05, ** p < 0.01