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. 2020 Mar 6;21(5):1836. doi: 10.3390/ijms21051836

Figure 1.

Figure 1

Experimental design and timeline.The mice were treated with once-daily d-galactose (d-gal) (150 mg/kg) or saline by subcutaneous injection for the first six weeks. From the fifth week, the vitamin E (VE) or Physalis alkekengi (PAE) groups were subjected to VE (100 mg/kg) or PAE (at doses of 3, 10, 30 mg/kg, oral) once daily for five weeks, and the control group and model group were administered a solvent (2% ethanol in oil, oral) in the same way instead. In the ninth week, the behavior tests were investigated after PAE administration. NOR, novel object recognition; WLFST, weight-loaded swimming test.