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. 2020 Feb 25;21(5):1558. doi: 10.3390/ijms21051558

Table 1.

Clusters and odors related to each cluster (Domain classification is based on Mori and Sakano [31]; summarized using Mori et al. [30] and Mori and Sakano [31]).

Domain Cluster Examples of the Odorous Chemical Compounds, which Activated the Cluster Odor Quality
Dorsal
(DI)
A Fatty acids and alkylamines [31]. Aliphatic acids, aliphatic aldehydes as well as “the subsets of these odorants with a similar carbon chain length” [30]. Diketones, benzaldehyde, and benzoic acid; common features are “a carboxyl group (-COOH), a diketone group (-(CO)(CO)-), or an ester group (-COO-)”. Fatty
Rancid
sour
pungent
Dorsal
(DII)
B Aliphatic alcohols, aliphatic ketones, and phenyl ethers [31]. “Aliphatic alcohols with relatively long carbon chain and to a wide range of aliphatic ketones”. Subsets of esters. Anisole and its derivatives with a methoxy group (-O-CH3). Combination “of elongated carbon chain structures with a hydroxyl group (-OH), an alkoxyl group (-O-R), or a carbonyl group (>C=O)”. Floral
Fruity
Green and grassy
Anisic
Dorsal
DII
C Phenols and phenyl ethers [31]. “Phenol family odorants, molecules having a hydroxyl group attached to the benzene ring”. Phenyl ethers; “molecular features of a benzene ring with hydroxyl group, a methoxy group, or an ethoxy group”. Phenolic
Medicinal
Spicy
Ethereal
D Aliphatic and aromatic ketones [31]; “responses to a variety of ketones: aliphatic ketones, aliphatic-aromatic ketones, diketones, and cyclic ketones”. Spicy
Minty
Lateral/ventral E Not specified in Mori et al. [30] nor in Mori and Sakano [31]; weak responses to ethers [30].
F Aliphatic “ketones, phenyl ethers, diketones, aliphatic-aromatic ketones, and cyclic ketones”.
G Phenyl “ethers, diketones, aliphatic ketones with relatively short side chains, aliphatic-aromatic ketones, cyclic ketones and ethers”.
H “Benzene-family odorants”. No response “or only a weak response to cyclic terpene hydrocarbons”. Some “respond to open-chain hydrocarbons”. “benzene derivatives with a polar functional group, such as anisole”, phenol, benzaldehyde, or acetophenone. Gassy and kerosene-like odor
I respond to at least one of the cyclic terpene hydrocarbons”. Subset of benzene-family odorants; cyclic terpene ketones, cyclic terpene alcohols Citrusy
Woody
Dorsal
DII
J Thiazoles and thiazolines [31].

*: Cited parts (““) are from Mori et al. [30].