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. 2020 Feb 27;21(5):1625. doi: 10.3390/ijms21051625
AAV Adeno-associated viral vector
ATP Adenosine triphosphate
BSG Basigin
BSG1 Basigin-1 with three immunoglobulin domains
BSG2 Basigin-2 with two immunoglobulin domains
CBA Chicken beta-actin
cGMP Cyclic guanosine monophosphate
CMV Cytomegalovirus
CNTF Ciliary neurotrophic factor
COS-1 Immortalizing CV-1 cell line
CsCl Cesium chloride
CSNB Congenital stationary night blindness
CX3CL1 C-X3-C motif chemokine ligand 1 or fractalkine
DHAP Dihydroxyacetone phosphate
EMA European Medicines Agency
ERG Electroretinogram
FDA Food and Drug Administration
G3P Glycerol-3-phosphate
G3PDH Glycerol-3-phosphate dehydrogenase
G6P Glucose-6-phosphate
GFP Green fluorescent protein
GLP Good laboratory practices
GLUT1 Glucose transporter SLC2A1
GMP Good manufacturing practice
GNAT1 rod transducin alpha subunit
HEK293 Human embryonic kidney 293 cell line
HDAC4 Histone deacetylase 4
Ig Immunoglobulin domain
ITRs Invert terminal repeats
KLF15 Krüppel-like factor 15
LACT Lactate
LCA Leber congenital amaurosis
LCA2 Leber congenital amaurosis with a mutation in the RPE65 gene
LCR Locus control region
LDH Lactate dehydrogenase
LRAT Lecithin-retinol acyltransferase
MTCs Lactate transporters
MPC Mitochondrial pyruvate carrier
NADPH Nicotinamide adenine dinucleotide phosphate, reduced
NHPs Non-human primates
NXNL1 Nucleoredoxin-like 1gene
OPN1L/MW Long and middle wave opsin gene
OXPHO Oxidative phosphorylation
PDE6B Phosphodiesterase 6B
PPP Pentose phosphate pathway
PRPF31 Pre-mRNA processing factor 31
PUFA Poly-unsaturated fatty acids
PYR Pyruvate
qPCR Quantitative polymerase chain reaction
RB1 Tumor suppressor retinoblastoma 1
rd1 Retinal degeneration 1 mutant
RdCVF Rod-derived cone viability factor
RdCVFL Thioredoxin enzyme rod-derived cone viability factor long
ROS Reactive oxygen species
RP Retinitis pigmentosa
RPE Retinal pigmented epithelium
RPE65 Retinal pigment epithelium protein of 65 kDa
SD-OCT Spectral domain optical coherence tomography
SV40T Simian virus 40 large T antigen
TCA Tricarboxylic acid cycle
TXNRD Thioredoxin reductase