Gemcitabine-eluting membrane (GEM) implantation suppresses the epithelial–mesenchymal transition (EMT) in xenograft tumors. (A,B) Transwell migration and invasion assays of SCK and PANC-1 cells. (C,D) Western blot analysis of E-cadherin, N-cadherin, snail, and vimentin expression at the bottom and top of SCK and PANC-1 tumor tissues after implantation with the GEM containing the indicated concentrations of gemcitabine. (E) Results of representative immunofluorescence analyses of E-cadherin, N-cadherin, snail, and vimentin in tissues from SCK tumors implanted with the GEM or control membrane.