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Myogenic effect of compounds 1–8 isolated from PC. (A) Structures of 1–8. (B) Transiently transfected C2C12 cells with a MyoD-responsive reporter gene were differentiated in the presence of each compound (100 nM), followed by measurement of luciferase activity. Data are expressed as mean ± S.D. of three independent experiments. RLU: relative luciferase units. NC: negative control (DMSO) and 1–8: compounds 1–8. Means without a common superscript differ significantly (p < 0.05).
