Skip to main content
. 2020 Feb 26;21(5):1597. doi: 10.3390/ijms21051597

Figure 1.

Figure 1

Assigning selected Best vitelliform macular dystrophy (BD)-, autosomal dominant vitreoretinochoroidopathy (ADVIRC)-, and autosomal recessive bestrophinopathy (ARB)-associated mutations to the chicken BEST1 structure. Crystal structure model of the homo-pentameric chicken BEST1 chloride channel [18]. Positions of BD- (red), ADVIRC- (green), and ARB- (blue) associated BEST1 mutations are indicated. Genotype-specific mutations were selected according to defined criteria (see Materials and Methods) and are given in Supplementary Table S1.