Table 1.
Different gastropod species MTs (left column) with abundance of amino acid residues (in single-letter codes) that are supposed to influence the metal-specific binding character of the respective MT proteins. The abundance of the selected amino acids refers to confirmed Cd- and Cu-specific gastropod MTs and snail md-MTs. The number (#) of selected amino acids (C, K, N, H) and the percentage (%) of charged amino acids (caas) in relation to the whole amino acid length (last column) of the respective MT peptide sequences (including the M at the start position) are listed. GenBank entry numbers are as follows: H.p. CdMT: AAK84863.1; C.a. CdMT: ABL73910.1; L.l. CdMT: AST14863.1; H.p. CuMT: AAK84864.1; C.a. CuMT: ABM55268.1, A.b. md-MTs (9md-MT: MK648139; 10md-MT: MK648140).
| MT | # of C | K/N Ratio | # of H | # caas | % caas | Length |
|---|---|---|---|---|---|---|
| Helix pomatia CdMT | 18 | 9/1 | 0 | 16 | 23.90 | 67 |
| Cornu aspersum CdMT | 18 | 8/2 | 0 | 14 | 20.90 | 67 |
| Littorina littorea CdMT | 27 | 10/2 | 0 | 21 | 21 | 100 |
| Alinda biplicata 9md-MT | 81 | 36/10 | 0 | 66 | 23 | 287 |
| Alinda biplicata 10md-MT | 90 | 40/13 | 0 | 74 | 23.20 | 319 |
| Alinda biplicata CuMT | 17 | 6/6 | 1 | 11 | 16.90 | 65 |
| Helix pomatia CuMT | 18 | 5/6 | 1 | 12 | 18.50 | 65 |
| Cornu aspersum CuMT | 17 | 3/9 | 1 | 11 | 16.90 | 65 |