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. 2020 Mar 7;21(5):1846. doi: 10.3390/ijms21051846

Figure 5.

Figure 5

Treatment with high-dose DEX significantly reduced serum triglyceride and non-esterified fatty acid (NEFA) levels, and increased serum glucose levels in tumor-bearing mice. Quantification of serum glucose (A), triglycerides (B), and NEFAs (C) in tumor-bearing mice (n = 3 mice per group) after treatment with 0.9% NaCl and 50 mg/kg DEX. (D,E) The expressions of proliferator-activated receptor α (Pparα), retinoid X receptor alpha (RXRA), and peroxisomal acyl-coenzyme A oxidase 1 (ACOX1) were determined via qPCR or Western blotting of livers taken from C57BL/6 mice treated with 0.9% NaCl or 50 mg/kg DEX. All data are presented as mean ± SEM and p < 0.05 is considered significant (*p < 0.05, **p < 0.01, ***p < 0.001; n = 3 mice per group). Results are representative of three independent experiments.