Ca2+	Calcium
CalDAG-GEF	Ca2+ and DAG-activated GEF
cAMP	cyclic adenosine monophosphate
CICR	Ca2+-induced Ca2+ release
CLL	chronic lymphocytic leukemia
CNS	central nervous system
CREB	cAMP-response element binding protein
eNOS	endothelial nitric oxide synthase
Epac	exchange protein activated by cAMP
ERK	extracellular signal-regulated kinase-1
GAPs	GTPase-activating proteins
GEFs	guanine nucleotide exchange factors
GPCR	G protein coupled receptor
IP3	inositol 1,4,5-trisphosphate
MAPK	mitogen-activated protein kinase
NO	nitric oxide
PDEs	phosphodiesterases
PIP	phosphatidyl inositol phosphate
PKA	protein kinase A
PLC	phospholipase C
REM	Ras exchange motif
RIAM	Rap1-GTP-interacting adaptor molecule
RLC20	myosin regulatory light chain
RyR	ryanodine receptor
SERCA	sarcoendoplasmic reticulum Ca2+-ATPase
TKR	tyrosine kinase receptors
TLR	Toll-like receptor
VEGFR2	vascular endothelial growth factor receptor 2