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Activation of caspase 3/7 in CRC cell lines after a 24 h-(A) and 48 h-(B) treatment with NEM or CP (IC50/72 h). The caspase 3/7 activity is expressed as percentage of fold change with respect to untreated cells. The values are normalized to the amount of living cells. Data are expressed as mean ± S.D. of three independent experiments. HT-29 cells: ** p < 0.01, **** p < 0.0001 vs. untreated cells. LoVo cells: ### p < 0.001, #### p < 0.0001 vs. untreated cells.
