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. 2020 Mar 7;21(5):1841. doi: 10.3390/ijms21051841

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© 2020 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).

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Lamin B1 in pyramidal hippocampal neurons. Low-intensity Lamin B1 immunopositivity is present at all conditions studied (A–J), with slightly higher levels at AD V-VI (E–J). Low-intensity Lamin B1 immunopositivity is present at all conditions studied (A–J), with slightly higher levels at AD V-VI, oligodendrocytes and microglia intensely stained (E,J). Lamin B1 did not present quantitative changes across the different conditions (K-M). Each point represents the image analysis of 50 cells per subject in CA1 and CA3 regions. Graphs express mean ± SD, * p < 0.05. See the text for further details of image analysis and statistics.