Table 4.
Multiple mixed-effect linear regression models between sleep onset time and cardiometabolic biomarkers stratified by sleep duration
| Less than 8 h (n = 837) | |||||
|---|---|---|---|---|---|
| Triglycerides β (95%CI) | Total cholesterol β (95%CI) | HDL β (95%CI) | LDL β (95%CI) | FPG# β (95%CI) | |
| Model 1 | 0.09(−0.04,0.22) | − 0.02(− 0.10,0.06) | −0.04(− 0.07,-0.01)** | −0.02(− 0.09,0.05) | −0.003(− 0.04,0.04) |
| Model 2 | 0.07(− 0.06,0.20) | −0.03(− 0.11,0.05) | −0.04(− 0.07,-0.01)* | −0.03(− 0.10,0.04) | −0.001(− 0.04,0.04) |
| Model 3 | 0.08(− 0.04,0.21) | −0.03(− 0.12,0.05) | −0.04(− 0.07,-0.01)** | −0.03(− 0.10,0.04) | −0.002(− 0.04,0.04) |
| 8 h and longer (n = 1581) | |||||
| Triglycerides β (95%CI) | Total cholesterol β (95%CI) | HDL β (95%CI) | LDL β (95%CI) | FPG# β (95%CI) | |
| Model 1 | 0.16 (0.09,0.24)** | 0.10(−6.21,6.41) | −0.06(− 0.08,-0.04)** | 0.10 (0.05,0.14)** | − 0.02(− 0.04,0.01) |
| Model 2 | 0.15 (0.07,0.23)** | 0.55(−5.91,7.02) | − 0.06(− 0.08,-0.04)** | 0.09 (0.04,0.13)** | −0.02(− 0.04,0.01) |
| Model 3 | 0.13 (0.05,0.20)** | 0.48(− 5.99,6.95) | − 0.05(− 0.07,-0.03)** | 0.08 (0.04,0.12) ** | −0.02(− 0.04,0.01) |
Model 1: sleep onset time + demographic characteristics (age, gender, ethnicity, education, marital status, occupation, economic condition); Model 2: Model 1 + health-related behaviors (smoking, alcohol use, tea drinking, physical exercise); Model 3: Model 2 + physical health (diabetes mellitus, hypertension, BMI)
# The model does not include diabetes mellitus; ** p < 0.01 *p < 0.05; β: beta coefficient; 95%CI: 95% confident interval, HDL High-density lipoprotein cholesterol, LDL low-density lipoprotein cholesterol, FPG fasting plasma glucose, All the β are for sleep onset time