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. 2020 Feb 24;17(5):664–677. doi: 10.7150/ijms.41999

Table 3.

Crucial and hub target genes in the miRNA-target network (degree >4)

Crucial Target Gene Description Degree
CPLX2 Complexin-2 8
GRIN2B Glutamate receptor ionotropic, NMDA 2B 8
KCNJ6 G protein-activated inward rectifier potassium channel 2 8
KSR2 Kinase suppressor of Ras 2 8
SYNGAP1 Ras/Rap GTPase-activating protein SynGAP 8
THRA Thyroid hormone receptor alpha 8
AGAP2 Arf-GAP with GTPase, ANK repeat and PH domain-containing protein 2 7
PTCH1 Protein patched homolog 1 7
SEMA4G Semaphorin-4G 7
VAMP2 Vesicle-associated membrane protein 2 7
CDK6 Cyclin-dependent kinase 6 6
CRTC2 CREB-regulated transcription coactivator 2 6
PAK6 Serine/threonine-protein kinase PAK 6 6
PRKCA Protein kinase C alpha type 6
ATP2B2 Plasma membrane calcium-transporting ATPase 2 5
CACNB3 Voltage-dependent L-type calcium channel subunit beta-3 5
FLNB Filamin-B 5
PPP1R12B Protein phosphatase 1 regulatory subunit 12B 5
SLC8A1 Sodium/calcium exchanger 1 5
VPS37D Vacuolar protein sorting-associated protein 37D 5