Table 3.
Frequency, site of first recurrence, and first salvage treatment modality for 2010 AJCC stage IVA ~ IVB local and regional recurrences
| IC group | CCRT group | |||
|---|---|---|---|---|
| (n = 44) | (n = 64) | |||
| No. | % | No. | % | |
| First failure site | ||||
| Local | 6 | 13.6 | 12 | 18.8 |
| Regional | 1 | 2.3 | 6a,b, c | 9.4 |
| Distant | 4 | 9.1 | 15 | 23 |
| First treatment modality for locoregional relapse | ||||
| Surgery ± Ctx | 2 | 28.6 | 2 | 11.8 |
| RT ± Ctx | 2 | 28.6 | 10 | 58.8 |
| CTx | 3 | 42.9 | 1 | 5.9 |
| Nil | 0 | 2 | 11.8 |
IC + CCRT: induction chemotherapy + concurrent chemoradiation; CCRT: concurrent chemoradiation; aOne patient had regional recurrence and mediastinal metastases concurrently and the other had regional and lung metastases simultaneously; bOne patient had regional recurrence and lung metastases concurrently; cOne patient had local and regional relapse and liver metastasis concurrently; Ctx: chemotherapy; RT: radiotherapy.