Table 1.
Mean ion signal intensity and the signal to background Ratio ratio for each drug; ND= not detectable
| Mean ion signal intensity | Signal to Background Ratio | ||||||
|---|---|---|---|---|---|---|---|
| pmol/ spot | AuNPs | TiO2 NPs | AuTiO2 NPs | AuNPs | TiO2 NPs | AuTiO2 NPs | |
| Niraparib | 100 | 277.5 | 149.5 | 1319.4 | 15.3 | 20.8 | 47.0 |
| 50 | 219.1 | 78.7 | 763.1 | 12.1 | 10.9 | 27.2 | |
| 20 | 86.9 | 66.7 | 445.1 | 4.8 | 9.3 | 15.8 | |
| 10 | 61.1 | 27.6 | 269.7 | 3.4 | 3.8 | 9.6 | |
| 5 | ND | ND | 155.3 | ND | ND | 5.5 | |
| Blank | 18.1 | 7.2 | 28.1 | ||||
| Olaparib | 100 | 745.2 | 613.5 | 4701.6 | 32.7 | 2.4 | 230.5 |
| 50 | 321.7 | 353.4 | 2490.1 | 14.1 | 1.4 | 122.1 | |
| 20 | 176.2 | ND | 673.1 | 7.7 | ND | 33.0 | |
| 10 | ND | ND | 271.4 | ND | ND | 13.3 | |
| 5 | ND | ND | 124.6 | ND | ND | 6.1 | |
| Blank | 22.8 | 253.2 | 20.4 | ||||