Figure 1.

MD2 expression is upregulated in human colon cancer. Human colon biopsy samples were prepared by immunohistochemical method for analysis; n=50. (A) Representative image stained by hematoxylin and eosin (H&E) showing normal adjacent colon tissue (left 2 panels) and colon cancer tissues (right 2 panels); boxed area indicates magnified area. (B) Representative images of immunochemical detection for MD2 (brown); normal adjacent colon tissue (left 2 panels) and colon cancer tissues (right 2 panels); boxed area indicates magnified area; scale bar = 100 µm. (C) Quantification of MD2 immunoreactivity of colon tissues as determined by Image J from colon biopsy samples. Data are shown as mean±SEM, n=50, ****P<0.0001 compared to normal colon tissues.