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. 2020 Mar 14;26:e920394-1–e920394-12. doi: 10.12659/MSM.920394

Figure 2.

Figure 2

Upregulation of microRNA-143 (miR-143) increased cardiac injury in response to doxorubicin toxicity. (A) Statistical findings on the efficacy of the miR-143 agomir in the mouse groups (n=6). (B) Functional parameters of murine hearts in the mouse groups (n=6). (C, D) Bodyweight and heart weight detection in the mouse groups (n=8). (E) Serum concentrations of cardiac troponin T (cTnT), lactate dehydrogenase (LDH) and creatine kinase myocardial band (CK-MB) isoenzyme in the mouse groups (n=6). Data are presented as the mean±standard deviation (SD) with the 95% confidence interval (CI). * P<0.05 versus the normal saline (NS)+antagomir control group. # P<0.05 versus the doxorubicin+antagomir control group. In Figure A, * P<0.05 versus the matched group.