Figure 2.
SC-Exos increase IENF density (IENFD). Representative images show PGP9.5-immunoreactive IENFs (red, arrows) in the hind plantar paw skin from nondiabetic mice (dm) (A), diabetic mice treated with saline (db) (B), and diabetic mice treated with SC-Exos (db+Exo) (C). Histogram represents the quantitative data of the IENFD under various conditions (D). Scale bar = 50 μm. n = 10 mice/group. *P < 0.05 vs. dm mice treated with saline; #P < 0.05 vs. db mice treated with saline.