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. 2020 Mar 5;17(6):799–806. doi: 10.7150/ijms.43832

Figure 1.

Figure 1

ME2 is expressed at a high level in oral squamous cell carcinoma. Representative hematoxylin-eosin (HE, left) and IHC (right) staining of ME2 in oral mucosal tissue(A) and in primary OSCC tissue(B). Scale bar: 50 μm. (C) Quantification of immunohistochemical histoscore of ME2 for oral mucosal tissue (n = 42), dysplasia tissue (DYS, n = 69) and primary oral squamous cell carcinoma tissue (OSCC, n = 176). (D) A Kaplan-Meier curve showing that OSCC patients with a low expression level of ME2 (n = 61) survive longer than patient with a high expression level of ME2 (n = 106), and log-rank analysis showed that the difference was significant (P < 0.05). (E) Western blot analysis the protein expression of ME2 in primary OSCC tissue and oral mucosal tissue. GAPHD was used as loading control.