Table 3.
Regions-of-interest showing significant differences in neural activation and cortico-striatal functional connectivity to Reward cue>No reward cue.
MNI | |||||||
---|---|---|---|---|---|---|---|
Coordinates |
|||||||
Region-of-interest | K | X | y | z | T | Z | Voxel p |
Neural Activation | |||||||
Right nucleus accumbens | 130 | 10 | 14 | −2 | 4.80 | 4.48 | <.001 |
Left insula | 172 | −32 | 0 | 12 | 4.39 | 4.13 | <.001 |
Left putamen | 32 | −14 | 6 | −6 | 4.36 | 4.11 | <.001 |
Right putamen | 32 | 26 | 10 | 4 | 4.11 | 3.90 | <.001 |
32 | 28 | −12 | 8 | 4.08 | 3.87 | <.001 | |
Left nucleus accumbens | 53 | −6 | 6 | −2 | 3.94 | 3.75 | <.001 |
Functional Connectivitya | |||||||
Right rACC | 111 | 4 | 34 | −8 | 4.80 | 4.48 | <.001 |
Left rACC | 71 | −4 | 30 | 0 | 4.11 | 3.90 | <.001 |
Note: k=number of voxels; rACC=rostral anterior cingulate cortex.
Nucleus accumbens served as the seed region: 6 mm sphere around the coordinates 12, 8, −6 (right hemisphere) −12, 8, −6 (left hemisphere) (Silverman et al., 2015).