Table 10. Correlation of NFIs with survival outcomes in esophageal cancer patients.
Gene | RNAseq ID | Survival outcome | No. of cases | Cut-off value | HR | 95% CI | p-Value |
---|---|---|---|---|---|---|---|
(A) Correlation of NFIs with survival outcomes in esophageal squamous cell carcinoma patients | |||||||
NFIA | 4774 | OS | 81 | 2,029 | 0.64 | [0.27–1.55] | 0.32 |
RFS | 54 | 1,211 | 0.57 | [0.22–1.49] | 0.25 | ||
NFIB | 4781 | OS | 81 | 2,102 | 0.51 | [0.21–1.24] | 0.13 |
RFS | 54 | 2,422 | 0.31 | [0.09–1.1] | 0.056 | ||
NFIC | 4782 | OS | 81 | 7,712 | 0.45 | [0.18–1.13] | 0.08 |
RFS | 54 | 9,377 | 1.45 | [0.53–3.91] | 0.47 | ||
NFIX | 4784 | OS | 81 | 4,135 | 0.72 | [0.3–1.73] | 0.46 |
RFS | 54 | 4,135 | 0.35 | [0.1–1.24] | 0.09 | ||
(B) Correlation of NFIs with survival outcomes in esophageal adenocarcinoma patients | |||||||
NFIA | 4774 | OS | 80 | 2,000 | 0.6 | [0.31–1.15] | 0.12 |
RFS | 19 | 2,161 | 6.57 | [0.66–65.46] | 0.068 | ||
NFIB | 4781 | OS | 80 | 2,571 | 1.46 | [0.76–2.79] | 0.25 |
RFS | 19 | 4,327 | 3.03 | [0.42–21.68] | 0.25 | ||
NFIC | 4782 | OS | 80 | 3,741 | 0.44 | [0.22–0.9] | 0.02 |
RFS | 19 | 3,579 | 271493742 | [0–lnf.] | 0.28 | ||
NFIX | 4784 | OS | 80 | 3,353 | 0.33 | [0.16–0.68] | 0.0017 |
RFS | 19 | 3373 | 0 | [0–lnf.] | 0.018 |
Note:
HR, hazard ratio; CI, confidence interval; OS, overall survival; RFS, relapse free survival.