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. 2020 Mar 18;8:e8816. doi: 10.7717/peerj.8816

Table 2. Correlation of NFIs with survival outcomes in breast cancer patients.

Gene Affymetrix ID Survival outcome No. of cases Cut-off value HR 95% CI p-Value
NFIA 226806_s_at OS 1,402 1,490 0.9 [0.65–1.22] 0.49
RFS 3,951 1,519 0.72 [0.61–0.84] <0.001
DMFS 1,746 1,484 0.94 [0.68–1.3] 0.72
PPS 414 1,488 1.03 [0.72–1.47] 0.88
NFIB 213029_at OS 1,402 1,292 0.94 [0.76–1.16] 0.56
RFS 3,951 1,216 1.1 [0.99–1.23] 0.086
DMFS 1,746 1,226 1.09 [0.9–1.32] 0.39
PPS 414 1,277 1.2 [0.94–1.53] 0.14
NFIC 226377_at OS 1,402 690 0.79 [0.58–1.08] 0.14
RFS 3,951 1,155 0.84 [0.72–0.98] 0.025
DMFS 1,746 1,005 0.85 [0.61–1.17] 0.31
PPS 414 657 1.36 [0.96–1.94] 0.086
NFIX 227400_at OS 1,402 585 0.71 [0.52–0.97] 0.033
RFS 3,951 723 0.82 [0.7–0.95] 0.0098
DMFS 1,746 684 0.96 [0.7–1.33] 0.81
PPS 414 539 0.92 [0.65–1.32] 0.67

Note:

HR, hazard ratio; CI, confidence interval; OS, overall survival; RFS, progression free survival; DMFS, distant metastasis free survival; PPS, post progression survival.