Table 4. Correlation of NFIs with survival outcomes in lung cancer patients.
| Gene | Affymetrix ID | Survival outcome | No. of cases | Cut-off value | HR | 95% CI | p-Value |
|---|---|---|---|---|---|---|---|
| NFIA | 226806_s_at | OS | 1,926 | 697 | 0.58 | [0.49–0.69] | <0.001 |
| FP | 982 | 981 | 0.69 | [0.53–0.9] | 0.0069 | ||
| PPS | 344 | 1,015 | 0.59 | [0.38–0.91] | 0.016 | ||
| NFIB | 213029_at | OS | 1,926 | 1,014 | 0.69 | [0.61–0.78] | <0.001 |
| FP | 982 | 1,179 | 0.9 | [0.74–1.09] | 0.28 | ||
| PPS | 344 | 1,237 | 0.66 | [0.52–0.86] | 0.0015 | ||
| NFIC | 226377_at | OS | 1,926 | 439 | 0.91 | [0.77–1.08] | 0.27 |
| FP | 982 | 464 | 1.16 | [0.88–1.51] | 0.29 | ||
| PPS | 344 | 426 | 1.7 | [1.1–2.62] | 0.016 | ||
| NFIX | 227400_at | OS | 1,926 | 339 | 0.97 | [0.82–1.14] | 0.72 |
| FP | 982 | 373 | 1.2 | [0.92–1.57] | 0.18 | ||
| PPS | 344 | 353 | 1.18 | [0.77–1.82] | 0.44 |
Note:
HR, hazard ratio; CI, confidence interval; OS, overall survival; FP, first progression; PPS, post progression survival.