Table 1. Results of the survey of the preclinical studies (n = 43).
| Requirement | Satisfied n (%) |
Not satisfied n (%) |
Unclear n (%) |
Not applicable n (%) |
|---|---|---|---|---|
| Sample size reported for the experiment? | 31 (72%) | 12 (28%) | - | - |
| Number of observations reported for the experiment? | 33 (77%) | 10 (23%) | - | - |
| Value of test statistics, exact p value and degrees of freedom reported? | 5 (12%) | 37 (86%) | - | 1 (2%) |
| Error bars correspond to the analysis (i.e. standard error is based on number of independent observations)? | 15 (35%) | 5 (12%) | 2 (5%) | 21 (48%) |
| Only independent observations were taken into account for statistical tests? | 31 (72%) | 6 (14%) | 6 (14%) | - |
| Is there negative control? | 33 (77%) | 4 (9%) | - | 6 (14%) |
| Was positive control necessary, and if so, was it used? | 29 (65%) | 9 (21%) | - | 6 (14%) |
| Were treatments randomly allocated to experimental units? | 17 (40%) | 21 (49%) | - | 5 (11%) |
| Number of citations: mean, standard deviation, median, interquartile range |
1.9 ± 2.1; 1.0; 3.0 | |||
| Time passed from the publication (years): mean, standard deviation, median, interquartile range | 4.7 ± 3.0; 4.0; 5.0 | |||
| Number of satisfied criteria per study: mean, standard deviation, median, interquartile range | 4.3 ± 1.8; 5.0; 2.0 | |||