Table 3.
Interaction test between age and tumor size on the risk of brain metastases from renal cell carcinoma.
| Age (years) | Tumor size (cm) | Crude | Model I | Model II |
|---|---|---|---|---|
| <70 | <7 | Ref. | Ref. | Ref. |
| ≥70 | <7 | 1.593 (0.915, 2.775), 0.1000 | 1.369 (0.780, 2.402), 0.2740 | 1.459 (0.837, 2.545), 0.1828 |
| <70 | ≥7 and <10 | 9.583 (6.540, 14.042), <0.0001 | 3.787 (2.499, 5.740), <0.0001 | 6.805 (4.574, 10.124), <0.001 |
| ≥70 | ≥7 and <10 | 6.221 (3.482, 11.114), <0.0001 | 2.569 (1.391, 4.742), 0.0026 | 4.363 (2.416, 7.879), <0.001 |
| <70 | ≥10 | 14.990 (10.336, 21.740), <0.0001 | 3.072 (2.006, 4.705), <0.0001 | 8.555 (5.709, 12.821), <0.001 |
| ≥70 | ≥10 | 8.252 (4.320, 15.761), <0.0001 | 2.159 (1.081, 4.314), 0.0293 | 4.868 (2.503, 9.470), <0.001 |
| P interaction | 0.0231 | 0.1679 | 0.0480 |
Model I was adjusted for bone metastasis, liver metastasis, and lung metastasis. Model II was adjusted for grade, N stage, marital status, race NEW, insurance, and Fuhrman grade.