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. Author manuscript; available in PMC: 2021 Feb 18.
Published in final edited form as: Vaccine. 2020 Jan 17;38(8):1915–1924. doi: 10.1016/j.vaccine.2020.01.027

Figure 7. The Chv proteins elicit production of potent bactericidal Ab.

Figure 7.

B. burgdorferi B31-HE-OspC was incubated with Chv hyperimmune serum as indicated in the figure with GPS serving as the exogenous complement source. To determine if Ab mediated killing is complement dependent, cells were incubated with hyperimmune serum and HI-GPS. Antisera generated against OspA served as a positive control for bactericidal activity. The One-Way ANOVA with post-hoc Tukey’s Multiple Comparison test was used to assess statistical significance (p<0.05). α-OspA served as the statistical reference.