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. Author manuscript; available in PMC: 2021 Jan 1.
Published in final edited form as: J Clin Lipidol. 2019 Nov 29;14(1):109–121.e5. doi: 10.1016/j.jacl.2019.11.005

Table 3.

Associations between baseline apo B, LDL-C, non-HDL-C and apo B concordance/discordance with LDL-C and non-HDL-C using residuals and medians with prevalent CAC >0 at baseline (N=4,623)

Minimally-adjusted1 Fully-adjusted2
N CAC>0/Total N Prevalence Ratio (95% CI) P Prevalence Ratio (95% CI) P
Individual Measures
Apo B Tertiles
 <96.9 mg/dl 637/1538 Ref Ref
 96.9 - 118.0 mg/dl 741/1540 1.13 (1.06, 1.20) <0.001 1.10 (1.04, 1.17) 0.002
 >118.0 mg/dl 807/1545 1.25 (1.17, 1.32) <0.001 1.21 (1.13, 1.29) <0.001
LDL-C Tertiles
 <106.0 mg/dl 648/1494 Ref Ref
 106.0 - 129.0 mg/dl 735/1537 1.11 (1.04, 1.17) <0.001 1.09 (1.03, 1.15) 0.005
 >129.0 mg/dl 802/1592 1.19 (1.12, 1.26) <0.001 1.17 (1.10, 1.24) <0.001
Non-HDL-C Tertiles
 <129.0 mg/dl 639/1512 Ref Ref
 129.0 - 136.0 mg/dl 733/1529 1.12 (1.05, 1.19) <0.001 1.09 (1.02, 1.15) 0.007
 >136.0 mg/dl 813/1582 1.21 (1.14, 1.29) <0.001 1.17 (1.09, 1.25) <0.001
Discordance by Residual7
Apo B/LDL-C
 Discordant Low 513/1194 0.95 (0.90, 1.01) 0.12 0.98 (0.92, 1.04) 0.46
 Concordant 1082/2287 Ref Ref
 Discordant High 590/1142 1.08 (1.02, 1.14) 0.01 1.02 (0.95, 1.08) 0.61
Apo B/non-HDL-C
 Discordant Low 496/1162 0.93 (0.88, 0.99) 0.03 0.93 (0.87, 0.99) 0.02
 Concordant 1118/2307 Ref Ref
 Discordant High 571/4623 1.05 (0.99, 1.12) 0.07 1.03 (0.98, 1.10) 0.24

Abbreviations: apolipoprotein B, apo B; coronary artery calcium, CAC; high-density lipoprotein cholesterol, HDL-C; low-density lipoprotein cholesterol, LDL-C; non-high-density lipoprotein cholesterol, non-HDL-C.

1

Prevalence ratio regression model adjusted for age, sex and race/ethnicity (White, Black, Chinese, Hispanic), smoking status, and hypertension.

2

Prevalence ratio regression model adjusted for age, sex, race/ethnicity (White, Black, Chinese, Hispanic), smoking status (never, former/current), hypertension (yes/no), body mass index, diabetes status (yes/no), triglycerides (log-transformed).

3

Discordant low=residual difference <25th percentile; discordant high=residual difference >75th percentile; concordant=residual difference 25th-75th percentile