Stains for neurons (MAP2) and astrocytes (GFAP). Immunohistochemical staining of the abnormal striatal nodules for neurons with an antibody to MAP2 showed abundant neuronal perikarya and fibers only within the left nodule (A, B). These were absent on the right nodule(C, D). The left nodule had abundant GFAP-immunoreactive astrocytic cell bodies and fibers. The right nodule showed positive fibers, consistent with a chronic astrocytic scar (G, H).
(A) MAP2 (2x) of left nodule (B) MAP2 (20x) on left nodule (C) MAP2 (2x) of right nodule (D) MAP2 (20x) on right nodule (E) GFAP (2x) of left nodule (F) GFAP (20x) on left nodule (G) GFAP (2x) of right nodule (H) GFAP (20x) on right nodule