Table 1.
Summary of immunohistochemistry for FOS and FOSB
| Tumor type | FOS positive* (%) | FOSB positive* (%) |
|---|---|---|
| Osteoid osteoma | 22/22 (100) | 0/22 |
| Osteoblastoma | 12/21 (57) | 2/21 (10) |
| Conventional osteosarcoma | 2/54 (4) | 1/55 (2) |
| Giant cell tumor of bone | 0/73 | 2/72 (3) |
| Aneurysmal bone cyst | 0/6 | 0/6 |
| Chondromyxoid fibroma | 0/19 | 0/19 |
| Chondroblastoma | 0/14 | 0/15 |
| Clear cell chondrosarcoma | 0/17 | - |
| Reactive bone with callus formation | 1/3 (33) | 0/2 |
| Proliferative bone lesion: | 0/11 | 5/8 (63) |
| Subungual exostosis | 0/3 | - |
| Bizarre parosteal osteochondromatous proliferation | 0/5 | 4/5 (80) |
| Myositis ossificans | 0/3 | 1/3 (33) |
*defined as strong nuclear expression in > 50% of tumor cells