Table 3.
Summary of the diagnostic accuracy measures reported for the TyG index.
| Study | Reference | TyG cutoff | Sensitivity (%) | Specificity (%) | PPV (%) | NPV (%) | PLR | NLR | DOR | AUC |
|---|---|---|---|---|---|---|---|---|---|---|
| Guerrero-Romero, [10] | HIEC | 4.68 | 96 | 85 | NR | NR | 6.4 | 0.05 | 136 | 0.85 |
| Guerrero-Romero, [12] | HIEC | 4.68M | 67M | 72M | 38M | 90M | 2.4M | 0.45M | 5.2M | 0.67M |
| 4.55F | 68F | 66F | 44F | 84F | 2.04F | 0.48F | 4.1F | 0.68F | ||
| Qu, [13] | HIEC | 4.55 | 67 | 72 | NR | NR | 2.4 | 0.46 | 5.22 | 0.77 |
| Almeda-Valdés, [5] | HIEC | 4.43 | 85.7 | 32.5 | 29.2 | 87.5 | 1.2 | 0.45 | 2.88 | 0.59 |
| Simental-Mendía, [7] | HOMA-IR | 4.65 | 84 | 45 | 81 | 84 | 1.5 | 0.36 | 4.29 | NR |
| Guerrero-Romero, [12] | HOMA-IR | 4.68M | 90.9 | 99.7 | 98.3 | 98.6 | NR | 0.09 | 3319.6 | NR |
| 4.55F | ||||||||||
| Mazidi, [17] | HOMA-IR | 4.78 | 75.9 | 71.9 | NR | NR | 2.7 | 0.34 | 8.05 | 0.81 |
| Dorota-Łojko, [20] | HOMA-IR | 4.69 | 73.8 | 75.6 | NR | NR | 3.0 | 0.35 | 8.72 | 0.78 |
| Salazar, [21] | HOMA-2IR | 4.49 | 82.6 | 82.1 | NR | NR | 4.6 | 0.21 | 21.77 | 0.88 |
M: male; F: female; HC: hyperglycemic clamp; HIEC: hyperinsulinemic-euglycemic clamp; TyG: triglyceride/glucose index; PPV: positive predictive value; NPV: negative predictive value; PLR: positive likelihood ratio; NLR: negative likelihood ratio; DOR: diagnostic odds ratio; AUC: area under the curve; NR: not reported.