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. Author manuscript; available in PMC: 2020 Mar 22.
Published in final edited form as: Microb Pathog. 2019 Apr 25;132:87–99. doi: 10.1016/j.micpath.2019.04.034

Table 5.

Occurrence of iron and iron-siderophore transport proteins in ten Treponema species. Proteins marked in purple are pathogen-specific; those marked in green are specific to non-pathogens, and those in orange are present in both pathogens and non-pathogens. Polarity of transport is indicated in columns 3 and 4 where an X indicates that the transport process is uptake or efflux.

TCID Substrate Transported Uptake Efflux The Tpal Tpe Tpr Taz Tsu Tpar Tbr Tca Tpu
1.B.14.1.3 Fe3+-enterobactin X 0 0 0 1 0 0 0 0 0 0
1.B.14.1.4 Fe3+- catecholate X 0 0 0 0 1 0 0 0 0 0
1.B.14.3.6 Fe3+-enterobactin X 0 0 0 1 0 0 0 0 0 0
2.A.4.7.1 Fe2+ X 0 0 0 1 1 0 0 0 0 0
2.A.4.7.4 Fe2+ X 0 0 0 0 0 0 0 0 1 0
2.A.4.7.9 Fe2+ X 0 0 0 0 0 0 0 1 0 0
2.A.108.2.10 Fe2+ X 0 0 0 0 1 0 0 0 0 0
3.A.1.5.2 Heme X 3 0 3 0 0 0 0 0 0 2
3.A.1.9.1 Fe3+ X 2 0 2 0 0 0 0 0 0 1
3.A.1.14.1 Fe3+-citrate X 0 0 0 0 0 0 0 0 1 0
3.A.1.14.2 Fe3+-enterobactin X 1 0 0 0 0 1 0 0 0 0
3.A.1.14.3 Fe3+-hydroxamate X 0 0 0 0 0 0 0 1 0 0
3.A.1.14.4 Fe3+-chrysobactine X 0 0 0 1 0 0 0 0 0 0
3.A.1.14.7 Fe3+-hydroxamate X 1 0 2 0 0 0 0 0 0 1
3.A.1.14.10 Heme X 2 0 2 0 0 0 0 0 0 1
3.A.1.14.14 Fe3+, Fe3+-heme, Fe3+-ferrichrome X 1 0 0 0 0 0 0 0 0 0
3.A.1.14.15 Fe3+-bacillibactin X 0 0 2 0 0 0 0 0 0 0
3.A.1.14.17 Heme X 1 0 3 0 0 0 0 0 0 0
3.A.1.14.18 Heme X 0 0 1 1 0 0 0 0 0 0
3.A.1.14.19 Heme X 0 0 0 1 0 1 0 0 0 0
3.A.1.14.20 Heme X 0 0 1 0 0 0 0 0 0 0
3.A.1.15.6 Fe2+ X 0 0 0 0 0 1 0 0 0 0
3.A.1.15.8 Fe3+ X 4 4 4 0 0 0 4 1 0 4
3.A.1.15.12 Fe2+ X 0 1 1 0 0 0 0 0 0 0
3.A.1.20.1 Fe3+ X 0 0 0 1 0 0 0 0 0 0
3.A.1.20.3 Fe3+ X 1 0 0 1 0 0 0 1 0 0
3.A.1.21.1 Fe3+-yersiniabactin X 3 0 0 0 0 0 0 0 0 2
3.A.1.21.2 Fe3+-carboxymycobactin X 0 0 0 0 0 0 0 0 1 0
9.A.8.1.4 Fe2+ X 0 0 0 0 0 1 0 0 0 0
9.A.8.1.9 Fe2+ X 1 0 0 1 1 0 0 0 0 0
9.A.8.1.14 Fe2+ X 0 0 0 0 0 0 0 1 0 0