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Chromatograms of ramosetron hydrochloride (0.3 mg/100 mL) and midazolam hydrochloride (0.5 mg/100 mL) admixtures that were freshly prepared (A), exposed to 0.1 mol/L hydrochloric acid at 60°C for 5 hrs (B), exposed to 0.1 mol/L sodium hydroxide at 60°C for 5 hrs (C), and exposed to 3% hydrogen peroxide at 60°C for 5 hrs (D). Ramosetron hydrochloride eluted at 4.84 min (peak 1) and midazolam hydrochloride eluted at 9.08 min (peak 2).
