Figure 4.
Insulin tolerance test (ITT) in adult females from all genotypes after 20 weeks of HFD. A: ITT from all genotypes and maternal diets. B: AUC analysis for all genotypes and maternal diets. Con = Maternal Control Diet and HFD = Maternal HFD. A: Data were analyzed by repeated-measures, multi-factorial ANOVA with post-hoc Newman-Keuls test. B: Data were analyzed by a two-way ANOVA with post-hoc Newman-Keuls test. See Figure 1 for information on treatment categories and sample sizes. Letters denote comparison between WT and KO within the HFD-fed dam group and underlined letters denote comparison between KIKO and KO within the HFD-fed dam group. Asterisks denote comparison within genotype across maternal diets (a/* = P < .05; b/** = P < .01; c/*** = P < .001; d/**** = P < .0001).
