Table 6.
Concomitant expression of altered proteins in PART
| Group | n | Gender (M/F) | Age (year) | αS+* | TDP43+ | p62+ | TDP43+/p62+ | TDP43+/p62− | TDP43−/p62+ | TDP43−/p62− |
| PART | ||||||||||
| I | 20 | 14/6 | 70±12 | 0 (0) | 11 (55) | 11 (55) | 7 (35) | 4 (20) | 4 (20) | 5 (25) |
| II | 8 | 7/1 | 82±11 | 0 (0) | 5 (63) | 6 (75) | 5 (63) | 0 (0) | 1 (13) | 2 (25) |
| III | 10 | 4/6 | 82±7 | 1 (10) | 8 (80) | 7 (70) | 6 (60) | 2 (20) | 1 (10) | 1 (10) |
| IV | 8 | 7/1 | 81±11 | 1 (12) | 7 (88) | 8 (100) | 7 (88) | 0 (0) | 1 (12) | 0 (0) |
| All | 46 | 32/14 | 76±12 | 2 (4) | 31 (67) | 32 (70) | 25 (55) | 6 (13) | 7 (15) | 8 (17) |
| AD | 23 | 13/10 | 84±9 | 0 (0) | 19 (83) | 19 (83) | 18 (79) | 1 (4) | 1 (4) | 3 (13) |
Data are presented as mean±standard error (SE), number (percentage), or number. * αS-positive except Parkinson’s disease cases. PART, primary age-related taupathy; M, male; F, female; αS, α-synuclein; TDP43, transactive response DNA-binding protein 43; AD, Alzheimer’s disease