Table 3.
Functional enrichment analysis
| Pathway ID | Pathway description | Count | P-value | Genes |
| GO-BP | ||||
| GO:0045669 | Positive regulation of osteoblast differentiation | 4 | 0.004 615 969 | CEBPD, NPNT, JAG1, BMPR1B |
| GO:0001701 | In utero embryonic development | 5 | 0.020 901 560 | MAN2A1, HHEX, RRN3, PTPRR, TWIST1 |
| GO:0045892 | Negative regulation of DNA-templated transcription | 8 | 0.021 870 896 | HHEX, CEBPD, TRIM6, DACH1, ZBTB16, FOXD1, TWIST1, ZNF423 |
| GO:0006334 | Nucleosome assembly | 4 | 0.029 188 620 | H2BFS, HIST1H1C, HIST1H2BE, HIST1H4H |
| GO:0060087 | Relaxation of vascular smooth muscle | 2 | 0.033 125 732 | RGS2, GUCY1A3 |
| GO:0010389 | Regulation of G2/M transition of mitotic cell cycle | 2 | 0.049 279 109 | CCNB3, PKIA |
| GO:2000737 | Negative regulation of stem cell differentiation | 2 | 0.049 279 109 | TRIM6, JAG1 |
| GO-CC | ||||
| GO:0016324 | Apical plasma membrane | 7 | 0.004 174 384 | ADRB2, SI, FZD3, JAG1, SCNN1B, NHS, SLC1A1 |
| GO:0043235 | Receptor complex | 5 | 0.004 393 425 | PTPRB, ADRB2, NR3C2, BMPR1B, VLDLR |
| GO:0005887 | Integral component of plasma membrane | 14 | 0.031 795 756 | PTPRB, FXYD3, SLC2A10, EFNB2, TLR3, JAG1, TPBG, ADRB2, SLC16A6, NLGN4X, SCNN1B, BMPR1B, SLC1A1, HLA-DRA |
| GO:0000940 | Condensed chromosome outer kinetochore | 2 | 0.040 957 971 | SPDL1, SKA1 |
| GO-MF | ||||
| GO:0015293 | Symporter activity | 3 | 0.030 268 219 | SLC16A6, SLC16A9, SLC1A1 |
| GO:0042803 | Protein homodimerization activity | 9 | 0.040 796 847 | RBPMS2, XDH, HHEX, ADRB2, CEBPD, NLGN4X, ABAT, ZBTB16, TWIST1 |
| KEGG | ||||
| hsa04960 | Aldosterone-regulated sodium reabsorption | 3 | 0.019 200 921 | NR3C2, HSD11B2, SCNN1B |
GO-BP: gene ontology-biological process; GO-CC: gene ontology-cellular component; GO-MF: gene ontology-molecular function; KEGG: Kyoto encyclopedia of genes and genomes