Table 1. Complete blood count in shRNA Rpl5 and shRNA Ren mice treated with doxycycline.
RBC: red blood cells (P=0.13); Hb: hemoglobin (P=0.0008); HTC: Hematocrit (P=0.117); MCV: corpuscular volume (P=0.3); WBC: white blood cell (P=0.46); NE: neutrophils (P=0.34); LY: lymphocytes (P=0.27); MO: monocytes (P=0.15); EO: eosinophils (P=0.45); BA: basophils (P=0.15); PLT: platelet count (P=0.92). Graphpad T test calculator website has been used to determine the P values based on standard division.
| Parameter (Units) | shRNA Rpl5 (Mean Result, n=3) | shRNA Ren (Mean Results, n=3) | Normal Range |
|---|---|---|---|
| RBC (M/µL) | 5.7 ±0.4 | 8.3±1.3 | 6.36-9.42 |
| Hb (g/dL) | 5.9±0.3 | 11.3±0.5 | 11.0-15.1 |
| HTC (%) | 26.8±1.9 | 41.8±7.3 | 35.1-45.4 |
| MCV (fl) | 47.3±0.9 | 50.3±2.3 | 45.4-60.3 |
| WBC (K/µL) | 6.0±2.7 | 12.6±7.6 | 1.8-10.7 |
| NE (K/µL) | 1.0±0.2 | 4.2±3.0 | 0.1-2.4 |
| LY (K/µL) | 2.9±0.8 | 7.4±3.4 | 0.9-9.3 |
| MO (K/µL) | 0.07±0.005 | 0.54±0.66 | 0.0-0.4 |
| EO (K/µL) | 0.02±0.01 | 0.38±0.43 | 0.0-0.2 |
| BA (K/µL) | 0.01±0.0 | 0.17±0.09 | 0.0-0.2 |
| PLT (K/µL) | 674.3±292.3 | 626.3±349.7 | 592-2972 |