Table 1.
Human Adaptation for Swine and Avian IAV Sequences before the 2009 H1N1 Influenza Pandemic in Different Countries/Areas.
| Host | Country/Area, Adaptation ratio (%) (Number of adaptive/total sequences) |
|||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| PB2 | PB1 | PA | HA | NP | NA | |||||||
| Swine | JP | 100.0 (20/20) | US | 99.2 (397/400) | JP | 100.0 (19/19) | DK | 100.0 (21/21) | JP | 100.0 (20/20) | DK | 84.2 (32/38) |
| HK | 69.7 (85/122) | JP | 94.7 (18/19) | UK | 96.9 (62/64) | UK | 97.2 (69/71) | US | 97.3 (427/439) | KR | 68.8 (22/32) | |
| CN | 57.7 (45/78) | CA | 91.7 (44/48) | IT | 94.7 (18/19) | JP | 93.1 (27/29) | CA | 91.7 (44/48) | IT | 57.5 (23/40) | |
| US | 32.6 (125/384) | KR | 82.1 (23/28) | HK | 91.9 (136/148) | IT | 90.5 (38/42) | KR | 83.3 (20/24) | CA | 55.3 (26/47) | |
| CA | 31.1 (14/45) | HK | 78.1 (121/155) | TH | 77.8 (7/9) | DE | 87.8 (36/41) | HK | 78.6 (125/159) | UK | 53.0 (35/66) | |
| KR | 19.4 (6/31) | CN | 60.0 (48/80) | CN | 66.7 (42/63) | CA | 78.0 (39/50) | CN | 60.8 (59/97) | JP | 42.9 (12/28) | |
| UK | 11.1 (7/63) | UK | 9.2 (6/65) | KR | 59.3 (16/27) | HK | 60.2 (100/166) | IT | 19.4 (6/31) | US | 36.6 (158/432) | |
| IT | 7.4 (2/27) | IT | 7.4 (2/27) | DE | 52.6 (10/19) | CN | 59.6 (68/114) | UK | 12.1 (8/66) | DE | 32.6 (14/43) | |
| FR | 6.2 (1/16) | ES | 0.0 (0/16) | US | 48.6 (192/395) | US | 59.2 (274/463) | FR | 5.9 (1/17) | CN | 27.2 (25/92) | |
| DE | 0.0 (0/25b) | DE | 0.0 (0/33) | CA | 42.2 (19/45) | TH | 48.4 (15/31) | DE | 0.0 (0/30) | HK | 16.8 (46/274) | |
| Avian | US | 8.4 (190/2,266) | CA | 3.5 (17/479) | US | 33.2 (758/2,286) | AUS | 51.2 (22/43) | US | 1.7 (33/1,935) | JP | 7.0 (3/43) |
| CN | 5.0 (27/542) | US | 2.2 (51/2,282) | CA | 28.9 (129/446) | DE | 36.6 (15/41) | HK | 1.6 (1/63) | CN | 5.7 (23/407) | |
| CA | 3.4 (16/474) | CN | 0.4 (2/534) | NL | 26.7 (58/217) | RU | 19.5 (8/41) | CA | 0.2 (1/417) | TH | 3.0 (1/33) | |
| HK | 3.2 (2/62) | VN | 0.0 (0/89) | AUS | 17.0 (8/47) | CA | 18.2 (87/478) | IT | 0.0 (0/79) | TW | 2.6 (1/39) | |
| JP | 3.1 (2/65) | IT | 0.0 (0/91) | TW | 8.1 (3/37) | US | 17.5 (352/2,008) | VN | 0.0 (0/92) | HK | 1.9 (1/52) | |
| NL | 0.4 (1/225) | NL | 0.0 (0/219) | CN | 6.8 (30/440) | JP | 14.3 (10/70) | NL | 0.0 (0/209) | US | 1.7 (17/976) | |
| AUS | 0.0 (0/47) | SE | 0.0 (0/237) | DE | 6.2 (2/32) | NL | 13.4 (28/209) | SE | 0.0 (0/232) | SE | 1.6 (1/62) | |
| RU | 0.0 (0/47) | \ | \ | IL | 5.4 (2/37) | HK | 9.4 (6/64) | CN | 0.0 (0/522) | NL | 0.9 (1/106) | |
| TH | 0.0 (0/54) | \ | \ | JP | 4.8 (3/63) | SE | 8.5 (20/236) | \ | \ | CA | 0.5 (1/184) | |
| IT | 0.0 (0/82) | \ | \ | HK | 3.1 (2/64) | TW | 7.7 (3/39) | \ | \ | IL | 0.0 (0/36) | |
Countries/areas were abbreviated as Australia: AUS, Canada: CA, China: CN, Spain: ES, France: FR, Germany: DE, Denmark: DK, Hong Kong, China: HK, Israel: IL, Italy: IT, Japan: JP, South Korea: KR, Netherlands: NL, Russia: RU, Sweden: SE, Taiwan, China: TW, Thailand: TH, United Kingdom: UK, USA: US, Vietnam: VN.