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. 2020 Feb 11;19(4):2650–2660. doi: 10.3892/etm.2020.8512

Figure 2.

Figure 2

Steroid-free endoscopic responses after FMT in two cases. A 37-year-old woman with a six-year history of left-sided UC and acute colitis (diarrhea six times per day with bleeding and abdominal pain) was treated with 4 g oral 5-aminosalicylate and 40 mg prednisone per day. (A) Baseline endoscopic appearance of a 30 cm rectosigmoid active colitis: Total Mayo score=8 and endoscopic subscore=3. Arrows: Diffuse mucosal erosion with marked hyperemia, edema, hemorrhage and purulent secretions. (B) Endoscopic appearance at the end of week 4 after FMT: Total Mayo score=1, endoscopic subscore=1. Arrows: White scar formation. The patient displayed steroid-free clinical remission until the follow-up at 12 weeks post-FMT. A 61-year-old woman with a two-year history of left-sided UC and acute colitis (diarrhea five times per day with bleeding) was treated with 4 g oral 5-aminosalicylate and 40 mg prednisone per day. (C) Baseline endoscopic appearance of a 25 cm rectosigmoid active colitis: Total Mayo score=7 and endoscopic subscore=2. Arrows: Erosion, mucosal congestion and edema and a small amount of purulent discharge. (D) Endoscopic appearance at 4 weeks post-FMT; total Mayo score=1 and endoscopic subscore=0. Arrow: Mucosa is intact and the blood vessel texture is slightly blurred. After FMT, the patient was completely weaned off corticosteroids and maintained their clinical and endoscopic remission until week 4 post-FMT. FMT, fecal microbiota transplantation; UC, ulcerative colitis.