Table 3.
Univariate and Multivariate logistic regression analysis of risk factors associated with HCC recurrence
| Variables | Univariate analysis | Multivariate analysis | |||
|---|---|---|---|---|---|
| Odds ratio(95%CI) | P value | Odds ratio(95%CI) | P value | ||
| Recipient age(0 ≤50,1>50) | 1.21(0.51-2.77) | 0.609 | |||
| Recipient sex (0 female,1 male) | 1.66(0.37-7.65) | 0.421 | |||
| Hepatitis B(0 No, 1 Yes) | 0.51(0.16-2.55) | 0.367 | |||
| Cirrhosis(0 No,1 Yes) | 0.53(0.16-1.58) | 0.201 | |||
| Child-Pugh grade (0 Grade A, 1 Grade B+C) | 1.21(0.52-2.77) | 0.733 | |||
| Histologic grade (0 well+moderately, 1 poorly) | 3.01(0.81-10.55) | 0.123 | |||
| Pre-LT serum AFP level (0 ≤400ng/ml,1>400ng/ml) | 0.744(0.25-2.23) | 0.566 | |||
| TNM stage(0 stage1-2, 1 stage3-4) | 8.33(2.38-24.88) | 0.003 | 6.444(2.671-26.679) | 0.007 | |
| Tumor size(cm) (0<5, 1 ≥5) | 4.54(1.76-11.09) | 0.011 | |||
| Number of nodules (0<3, 1 ≥3) | 2.54(1.11-7.01) | 0.042 | |||
| Microvascular invasion(0 No, 1 Yes) | 14.12(4.54-47.12) | <0.001 | 20.283(3.277-125.527) | 0.001 | |
| Milan criteria(0 within, 1 beyond) | 7.44(2.32-23.01) | 0.002 | 5.924(1.379-25.446) | 0.017 | |
| Donor Rap1A rs494453 genotype (0 AA, 1 AG/GG) | 2.211(1.114-5.898) | 0.009 | 12.014(2.351-61.401) | 0.003 | |
CI: confidence interval.