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Effects of SPARC overexpression on M2-mediated anti-apoptosis ability. After treated with 5-fluorouracil at IC50 (1 µg/mL for BGC-823, SGC-7901, MKN-45 and 30 µg/mL for GES-1) for 48 hours, more apoptotic cells were observed by flow apoptosis detection in all four SPARC overexpression groups.
