Table 1.
The clinicopathological characteristics of 76 patients with gastric cancer
| Number (N) | Macrophage SPARC expression | P-value | ||
|---|---|---|---|---|
| High expression | Low expression | |||
| Sex | ||||
| Male | 59 | 30 (50.8%) | 29 (49.2%) | 0.118 |
| Female | 17 | 5 (29.4%) | 12 (70.6%) | |
| Age | ||||
| >50 years | 63 | 29 (46.0%) | 34 (54.0%) | 0.994 |
| ≤50 years | 13 | 6 (46.1%) | 7 (53.8%) | |
| Tumour Location | ||||
| Localized | 69 | 48 (69.6%) | 21 (30.4%) | 0.078 |
| Diffused | 7 | 2 (28.6%) | 5 (71.4%) | |
| Tumour Size (cm) | ||||
| <5 | 26 | 14 (53.8%) | 12 (46.2%) | 0.326 |
| ≥5 | 50 | 21 | 29 | |
| Histological type | ||||
| Adenocarcinoma | 49 | 23 (47%) | 26 (53%) | 0.835 |
| Other type | 27 | 12 (44.4%) | 15 (55.6%) | |
| Grade | ||||
| Well and Moderately differentiated | 14 | 4 (28.6%) | 10 (71.4%) | 0.303 |
| Poorly differentiated | 62 | 27 (43.5%) | 35(56.5%) | |
| Degree of invasion | ||||
| T1 | 3 | 3 (100%) | 0 | 0.5713 |
| T2 | 12 | 5 (41.7%) | 7 (58.3%) | |
| T3 | 34 | 15(44.1%) | 19 (55.9%) | |
| T4 | 27 | 12 (44.4%) | 15 (55.6%) | |
| Lymph node metastasis | ||||
| 0-6 | 43 | 25 (58.1%) | 18 (41.9%) | 0.017 |
| 7 or more | 33 | 10 (30.3%) | 23 (66.7%) | |
| Remote metastasis | 0.241 | |||
| No | 67 | 33 (49.3%) | 34 (50.7%) | |
| Yes | 9 | 2 (22.2%) | 7 (77.8%) | |
| TNM classification | ||||
| Ⅰ | 7 | 5 (71.4%) | 2 (28.6%) | 0.078 |
| Ⅱ | 12 | 6 (50%) | 6 (50%) | |
| Ⅲ | 48 | 22 (45.8%) | 26 (54.2%) | |
| Ⅳ | 9 | 2 (22.2%) | 7 (77.8%) | |
| Cancer embolus | ||||
| Yes | 45 | 24 (53.3%) | 21 (46.7%) | 0.125 |
| No | 31 | 11 (35.5%) | 20 (65.5%) | |
Categorical variables are expressed as percentages and compared using Pearson's chi-square or Fisher's exact test as appropriate.