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. 2020 Feb 20;11(10):2730–2736. doi: 10.7150/jca.36238

Table 5.

The cutoff value, sensitivity, specificity and AUC for single risk factor in predicting OM in male lung cancer patients

Factor Cut-off value Sensitivity (%) Specificity (%) AUC P
CA-125 (U/ml) 76.56 60.00 85.56 0.754 <0.001
CA-153 (U/ml) 22.33 70.00 82.76 0.790 <0.001
CYFRA21-1(ng/ml) 10.70 72.00 87.09 0.838 <0.001
CA-125+CA-153 - 74.00 81.89 0.827 <0.001
CA-125+CYFRA21-1 - 74.00 84.12 0.834 <0.001
CA-153+CYFRA21-1 - 80.00 80.45 0.850 <0.001
CA-125+CA-153+CYFRA21-1 - 82.00 82.92 0.859 <0.001

Notes: Sensitivity and specificity were obtained at the point of cutoff value. P <0.05 represented statistically significant. Abbreviations: AUC, area under the curve; CI, confidence interval; OM, ocular metastasis.