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. 2020 Feb 20;11(10):2730–2736. doi: 10.7150/jca.36238

Table 7.

The risk factors of metastases of male lung cancer

Author Year Histopathological type Metastatic sites Risk factor
Lina Wu et al 37 2017 NSCLC Lymph node MicroRNA-422a
Chu Y et al 38 2017 Adenocarcinoma Lymph node CLSTN1, CLU, NGAL
Brody R et al 39 2017 NSCLC NS PD-L1
Wu S et al 40 2016 NSCLC Lymph node B7-H3
Chen Y et al 41 2015 NSCLC Brain NSE
Jain L et al 42 2009 NS NS SNP
Oshiro Y et al43 2004 Adenocarcinoma Liver AFP
Nikliński J et al 44 1992 NSCLC Lymph node SCC
Hirashima T et al45 2000 NSCLC NS telomere
Pollán M et al46 2003 NSCLC NS CA-125
Zhou Y et al47 2017 NS Bone CA-125, ALP
Cedrés S et al 48 2011 NSCLC Brain CEA, CYFRA21-1,
Dan Liu et al 49 2017 Adenocarcinoma Brain, lymph node CA-125
Chen F et al50 2015 NS Lymph node CYFRA21-1, CEA
Lee DS et al51 2012 NSCLC Brain CEA
Morita S et al52 2019 NSCLC Intertrabecular Vertebral CEA
Shetty D et al53 2016 NSCLC Thyroid gland, lymph node PSMA

Abbreviations: NS, not specific; NSCLC, non-small cell lung cancer; SCC, squamous cell carcinoma antigen; CLSTN1, calsyntenin-1; CLU, clusterin; NGAL, neutrophil gelatinase-associated lipocalin; SNP, single nucleotide polymorphisms; PD-L1, programmed cell death-1; B7-H3, B7 homolog 3; PSMA, prostate-specific membrane antigen.