Table III.
The effect of Icariin on blood glucose level during the oral glucose tolerance test in T2DM rats.
| Blood glucose (mmol/l) | ||||||
|---|---|---|---|---|---|---|
| Groups | 0 min | 15 min | 30 min | 60 min | 120 min | |
| Control | 2.88±0.7 | 6.45±1.3 | 7.09±1.2 | 6.24±1.0 | 3.87±0.7 | |
| Diabetic | 5.89±1.1 | 12.3±1.8 | 19.3±1.0 | 20.51±1.1 | 3.83±1.8a | |
| Metformin | 3.16±0.9 | 8.23±1.7 | 9.63±1.4 | 7.98±1.3 | 3.82±1.1b | |
| Icariin 5 mg/kg | 5.48±1.3 | 8.70±1.3 | 12.88±1.8 | 13.86±2.1 | 9.83±2.3 | |
| Icariin 10 mg/kg | 4.02±1.2 | 10.31±1.9 | 11.41±0.9 | 10.87±1.5 | 5.31±1.3b | |
| Icariin 20 mg/kg | 3.27±0.7 | 8.29±1.7 | 9.81±1.6 | 8.68±1.8 | 4.03±1.8b | |
Values are means ± standard deviation.
aP<0.05 vs. the control group;
bP<0.05 vs. the diabetic group; n=10; T2DM, type 2 diabetes mellitus.