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. 2020 Feb 21;19(4):2913–2922. doi: 10.3892/etm.2020.8543

Figure 4.

Figure 4.

Role of β-catenin and Gli1 in A549 cell proliferation. (A) β-catenin expression was analyzed in the pcDNA3.1 empty vector, NC siRNA, β-catenin siRNA and β-catenin OX cells. Error bars indicate the mean ± SE (n=3). *P<0.05 and **P<0.01 vs. NC siRNA. (B) Cell proliferation rate was analyzed in the pcDNA3.1 empty vector, NC siRNA, β-catenin siRNA and β-catenin OX cells. *P<0.05 vs. NC siRNA. (C) Gli1 expression was analyzed in the pcDNA3.1 empty vector, NC siRNA, Gli1 siRNA and Gli1 OX cells. Error bars indicate the mean ± SE (n=3). *P<0.05 and **P<0.01 vs. pcDNA3.1 empty vector. (D) Cell proliferation rate in the pcDNA3.1 empty vector, NC siRNA, Gli1 siRNA and Gli1 OX cells. Data represent the mean ± SE of 6 replicates. *P<0.05 vs. pcDNA3.1 empty vector. GLI, GLI family zinc finger; NC, non-targeting control; OD, optical density; OX, overexpression; siRNA, small interfering RNA.