Table 2.
Group effect | Group-by-age interaction Early adulthood | Group-by-age interaction Middle adulthood | |||||||||
---|---|---|---|---|---|---|---|---|---|---|---|
Cognitive measure | β | p | pFDR | β | p | pFDR | ΔES | β | p | pFDR | ΔES |
Affective psychosis | |||||||||||
g | −0.46 | <0.001 | <0.001 | 0.45 | 0.204 | 0.317 | 0.17 | 0.42 | 0.034 | 0.078 | 0.31 |
WTAR | −0.45 | <0.001 | <0.001 | 0.19 | 0.642 | 0.817 | −0.18 | 1.36 | <0.001 | <0.001 | 1.29 |
Vocabulary | −0.19 | 0.011 | 0.013 | −0.92 | 0.026 | 0.093 | −0.63 | 0.51 | 0.024 | 0.068 | 0.70 |
Matrix reasoning | −0.13 | 0.169 | 0.198 | 1.39 | 0.013 | 0.060 | 0.68 | 0.54 | 0.076 | 0.134 | 0.22 |
Semantic fluency | −0.44 | <0.001 | <0.001 | 0.64 | 0.144 | 0.288 | 0.11 | 1.17 | <0.001 | <0.001 | 1.01 |
Verbal fluency | −0.15 | 0.010 | 0.013 | −0.13 | 0.705 | 0.822 | −0.04 | −0.18 | 0.343 | 0.437 | −0.15 |
Trail-Making A | −0.43 | <0.001 | <0.001 | −0.33 | 0.318 | 0.445 | −0.15 | −0.17 | 0.330 | 0.437 | −0.10 |
Trail-Making B | −0.31 | <0.001 | <0.001 | 0.08 | 0.859 | 0.925 | 0.03 | 0.04 | 0.850 | 0.850 | 0.03 |
Digit-symbol coding | −0.44 | <0.001 | <0.001 | 0.76 | 0.008 | 0.057 | 0.32 | 0.54 | 0.001 | 0.003 | 0.36 |
CVLT recall | −0.54 | <0.001 | <0.001 | 1.34 | <0.001 | 0.001 | 0.60 | 0.77 | <0.001 | <0.001 | 0.45 |
CVLT recognition | −0.35 | <0.001 | <0.001 | 0.86 | 0.082 | 0.192 | 0.42 | 0.31 | 0.252 | 0.391 | 0.11 |
Span forward | −0.13 | 0.200 | 0.216 | 1.03 | 0.079 | 0.192 | 0.62 | −0.18 | 0.579 | 0.660 | −0.40 |
Span backward | 0.03 | 0.670 | 0.670 | 0.00 | 0.999 | 0.999 | −0.11 | 0.50 | 0.049 | 0.098 | 0.49 |
Letter-number sequencing | −0.44 | <0.001 | <0.001 | 0.79 | 0.174 | 0.305 | 0.42 | 0.16 | 0.613 | 0.660 | −0.02 |
Nonaffective psychosis | |||||||||||
g | −0.82 | <0.001 | <0.001 | −0.84 | 0.019 | 0.095 | −0.60 | 0.60 | 0.002 | 0.007 | 0.78 |
WTAR | −0.67 | <0.001 | <0.001 | −0.49 | 0.230 | 0.358 | −0.45 | 0.82 | <0.001 | 0.002 | 0.91 |
Vocabulary | −0.27 | <0.001 | <0.001 | 0.46 | 0.259 | 0.362 | 0.09 | 0.81 | <0.001 | 0.002 | 0.69 |
Matrix reasoning | −0.29 | 0.003 | 0.003 | 0.00 | 0.999 | 0.999 | 0.03 | −0.13 | 0.661 | 0.771 | −0.13 |
Semantic fluency | −0.45 | <0.001 | <0.001 | −0.04 | 0.932 | 0.999 | −0.15 | 0.61 | 0.011 | 0.026 | 0.61 |
Verbal fluency | −0.36 | <0.001 | <0.001 | −0.67 | 0.061 | 0.172 | −0.38 | 0.01 | 0.939 | 0.939 | 0.16 |
Trail-Making A | −0.58 | <0.001 | <0.001 | −0.42 | 0.195 | 0.358 | −0.19 | −0.24 | 0.185 | 0.323 | −0.14 |
Trail-Making B | −0.61 | <0.001 | <0.001 | −1.54 | <0.001 | 0.006 | −0.89 | 0.10 | 0.657 | 0.771 | 0.44 |
Digit-symbol coding | −0.63 | <0.001 | <0.001 | 0.63 | 0.027 | 0.095 | 0.30 | 0.22 | 0.156 | 0.313 | 0.08 |
CVLT recall | −0.50 | <0.001 | <0.001 | 0.01 | 0.979 | 0.999 | 0.31 | 1.28 | <0.001 | <0.001 | 1.26 |
CVLT recognition | −0.43 | <0.001 | <0.001 | 0.62 | 0.208 | 0.358 | −0.27 | 0.25 | 0.350 | 0.544 | 0.11 |
Span forward | −0.57 | <0.001 | <0.001 | 1.36 | 0.021 | 0.095 | 0.52 | 1.17 | <0.001 | 0.002 | 0.85 |
Span backward | −0.46 | <0.001 | <0.001 | 0.16 | 0.728 | 0.927 | 0.06 | 0.15 | 0.564 | 0.771 | 0.11 |
Letter-number sequencing | −0.65 | <0.001 | <0.001 | −0.94 | 0.107 | 0.250 | −0.53 | −0.03 | 0.919 | 0.939 | 0.18 |
Bolded estimates signify statistical significance (P < 0.05).
WTAR, Wechsler Test of Adult Reading; FDRCorrected for multiple testing (FDR = 0.05); ΔES, effect size of change (in S.D.).